Quantitation of sex-specific serum N-glycome changes in expression level during mouse aging based on Bionic Glycome method

J Han, Y Pan, W Qin, Y Gu, X Xu, R Zhao, J Sha… - Experimental …, 2020 - Elsevier
Studying the changes of serum N-glycome during mouse aging is beneficial to explore the
molecular basis behind the alterations reported in human. However, such studies
remainscarce and lack some information such as sialylation due to the method limitation.
Here, we introduced Bionic Glycome method to quantify the serum N-glycome changes
during C57BL/6 mouse aging (from the pubertal period to the old age stage). This technique
enabled reliable and comprehensive quantitation of the expression level changes of more …