[HTML][HTML] Simple diffusion-constrained immunoassay for p24 protein with the sensitivity of nucleic acid amplification for detecting acute HIV infection
L Chang, L Song, DR Fournier, CW Kan… - Journal of virological …, 2013 - Elsevier
Nucleic acid amplification techniques have become the mainstay for ultimate sensitivity for
detecting low levels of virus, including human immunodeficiency virus (HIV). As a
sophisticated technology with relative expensive reagents and instrumentation, adoption of
nucleic acid testing (NAT) can be cost inhibited in settings in which access to extreme
sensitivity could be clinically advantageous for detection of acute infection. A simple low cost
digital immunoassay was developed for the p24 capsid protein of HIV based on trapping …
detecting low levels of virus, including human immunodeficiency virus (HIV). As a
sophisticated technology with relative expensive reagents and instrumentation, adoption of
nucleic acid testing (NAT) can be cost inhibited in settings in which access to extreme
sensitivity could be clinically advantageous for detection of acute infection. A simple low cost
digital immunoassay was developed for the p24 capsid protein of HIV based on trapping …