[HTML][HTML] Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis
SA Khan, EE Wollaston-Hayden, TW Markowski… - Journal of lipid …, 2015 - ASBMB
Hepatic steatosis is characterized by the accumulation of lipid droplets (LDs), which are
composed of a neutral lipid core surrounded by a phospholipid monolayer embedded with
many proteins. Although the LD-associated proteome has been investigated in multiple
tissues and organisms, the dynamic changes in the murine LD-associated proteome in
response to obesity and hepatic steatosis have not been studied. We characterized the
hepatic LD-associated proteome of C57BL/6J male mouse livers following high-fat feeding …
composed of a neutral lipid core surrounded by a phospholipid monolayer embedded with
many proteins. Although the LD-associated proteome has been investigated in multiple
tissues and organisms, the dynamic changes in the murine LD-associated proteome in
response to obesity and hepatic steatosis have not been studied. We characterized the
hepatic LD-associated proteome of C57BL/6J male mouse livers following high-fat feeding …