microRNAs and the immune response
MA Lindsay - Trends in immunology, 2008 - cell.com
Trends in immunology, 2008•cell.com
microRNA (miRNA)-mediated RNA interference has been identified as a novel mechanism
that regulates protein expression at the translational level. Recent publications have
provided compelling evidence that a range of miRNAs are involved in the regulation of
immunity, including the development and differentiation of B and T cells, proliferation of
monocytes and neutrophils, antibody switching and the release of inflammatory mediators.
In this review, we examine what is presently known of the function and mechanism of action …
that regulates protein expression at the translational level. Recent publications have
provided compelling evidence that a range of miRNAs are involved in the regulation of
immunity, including the development and differentiation of B and T cells, proliferation of
monocytes and neutrophils, antibody switching and the release of inflammatory mediators.
In this review, we examine what is presently known of the function and mechanism of action …
microRNA (miRNA)-mediated RNA interference has been identified as a novel mechanism that regulates protein expression at the translational level. Recent publications have provided compelling evidence that a range of miRNAs are involved in the regulation of immunity, including the development and differentiation of B and T cells, proliferation of monocytes and neutrophils, antibody switching and the release of inflammatory mediators. In this review, we examine what is presently known of the function and mechanism of action of these miRNAs in the regulation of the innate and acquired immune response.
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