[HTML][HTML] The possible role of virus-specific CD8+ memory T cells in decidual tissue
A Van Egmond, C Van Der Keur, G Swings… - Journal of reproductive …, 2016 - Elsevier
The most abundant lymphocyte present in decidual tissue is the CD8+ T cell. It has been
shown that most decidual CD8+ T cells have an effector-memory phenotype, but expressed
reduced levels of perforin and granzyme B compared with the peripheral CD8+ effector-
memory T cells. The specificity of these CD8+ memory T cells has yet to be determined. One
hypothesis is that the decidual memory T cells are virus-specific T cells that should protect
the fetus against incoming pathogens. As virus-specific CD8+ memory T cells can cross …
shown that most decidual CD8+ T cells have an effector-memory phenotype, but expressed
reduced levels of perforin and granzyme B compared with the peripheral CD8+ effector-
memory T cells. The specificity of these CD8+ memory T cells has yet to be determined. One
hypothesis is that the decidual memory T cells are virus-specific T cells that should protect
the fetus against incoming pathogens. As virus-specific CD8+ memory T cells can cross …
