The immunological basis of villitis of unknown etiology–review

JA Tamblyn, DM Lissauer, R Powell, P Cox, MD Kilby - Placenta, 2013 - Elsevier
Villitis of unknown etiology (VUE) represents a common placental inflammatory lesion,
primarily, but not exclusively, identifiable T lymphocytes at term. Despite considerable
evidence to contest that this simply represents a benign pathological finding, VUE remains a
significantly undervalued diagnosis. Given its association with adverse pregnancy
outcomes; including fetal growth restriction, preterm birth, and recurrent pregnancy loss, an
increased awareness amongst clinician obstetricians is certainly warranted. The underlying …