Net reclassification indices for evaluating risk prediction instruments: a critical review

KF Kerr, Z Wang, H Janes, RL McClelland… - …, 2014 - journals.lww.com
Net reclassification indices have recently become popular statistics for measuring the
prediction increment of new biomarkers. We review the various types of net reclassification
indices and their correct interpretations. We evaluate the advantages and disadvantages of
quantifying the prediction increment with these indices. For predefined risk categories, we
relate net reclassification indices to existing measures of the prediction increment. We also
consider statistical methodology for constructing confidence intervals for net reclassification …