Prospective evaluation of the prevalence of non-alcoholic fatty liver disease and steatohepatitis in a large middle-aged US cohort

SA Harrison, S Gawrieh, K Roberts, CJ Lisanti… - Journal of …, 2021 - Elsevier
Background & Aims Large prospective studies to establish the prevalence of non-alcoholic
fatty liver disease (NAFLD) and steatohepatitis (NASH), are lacking. We prospectively
assessed the prevalence and severity of NAFLD/NASH in a cohort of asymptomatic middle-
aged Americans attending a colonoscopy class at a gastroenterology clinic. Methods
Screening for NAFLD was performed using magnetic resonance (MR)-based
LiverMultiScan® proton density fat fraction (LMS-PDFF). MR exams also included corrected …