Sex, age, anatomic location, and extent of resection influence outcomes in children with high-grade glioma
BACKGROUND: Survival duration and prognostic factors in adult high-grade glioma have
been comprehensively analyzed, but less is known about factors contributing to overall
survival (OS) and progression-free survival (PFS) in pediatric patients. OBJECTIVE: To
identify these factors in the pediatric population. METHODS: We retrospectively reviewed
institutional databases evaluating all patients≤ 21 years with high-grade glioma treated
between 1988 and 2010. Kaplan-Meier curves and log-rank statistics were used to compare …
been comprehensively analyzed, but less is known about factors contributing to overall
survival (OS) and progression-free survival (PFS) in pediatric patients. OBJECTIVE: To
identify these factors in the pediatric population. METHODS: We retrospectively reviewed
institutional databases evaluating all patients≤ 21 years with high-grade glioma treated
between 1988 and 2010. Kaplan-Meier curves and log-rank statistics were used to compare …