Fatty acid synthase over expression is an indicator of tumor aggressiveness and poor prognosis in renal cell carcinoma
A Horiguchi, T Asano, T Asano, K Ito, M Sumitomo… - The Journal of …, 2008 - Elsevier
PURPOSE: Fatty acid synthase is a key enzyme in the de novo biosynthesis of fatty acids.
Increased fatty acid synthase expression and its association with tumor aggressiveness and
poor prognosis have been demonstrated in various human malignant tumors. We
investigated fatty acid synthase expression in patients with renal cell carcinoma and its
impact on clinicopathological parameters. MATERIALS AND METHODS: Fatty acid synthase
expression in 120 patients with renal cancer was examined by immunohistochemistry. The …
Increased fatty acid synthase expression and its association with tumor aggressiveness and
poor prognosis have been demonstrated in various human malignant tumors. We
investigated fatty acid synthase expression in patients with renal cell carcinoma and its
impact on clinicopathological parameters. MATERIALS AND METHODS: Fatty acid synthase
expression in 120 patients with renal cancer was examined by immunohistochemistry. The …