[HTML][HTML] COX15 codes for a mitochondrial protein essential for the assembly of yeast cytochrome oxidase
DM Glerum, I Muroff, C Jin, A Tzagoloff - Journal of Biological Chemistry, 1997 - ASBMB
The respiratory defect of Saccharomyces cerevisiae mutants assigned to complementation
group G4 of apet strain collection stems from their failure to synthesize cytochrome oxidase.
The mutations do not affect expression of either the mitochondrially or nuclearly encoded
subunits of the enzyme. The cytochrome oxidase deficiency also does not appear to be
related to mitochondrial copper metabolism or heme abiosynthesis. These data suggest that
the mutants are likely to be impaired in assembly of the enzyme. A gene designated …
group G4 of apet strain collection stems from their failure to synthesize cytochrome oxidase.
The mutations do not affect expression of either the mitochondrially or nuclearly encoded
subunits of the enzyme. The cytochrome oxidase deficiency also does not appear to be
related to mitochondrial copper metabolism or heme abiosynthesis. These data suggest that
the mutants are likely to be impaired in assembly of the enzyme. A gene designated …
