[HTML][HTML] Safety of< 7500 RE (< 25000 IU) vitamin A daily in adults with retinitis pigmentosa
L Sibulesky, KC Hayes, A Pronczuk… - The American journal of …, 1999 - Elsevier
Background Vitamin A supplementation is being used successfully to treat some forms of
cancer and the degenerative eye disease retinitis pigmentosa. The daily biological need for
vitamin A is estimated to be 800 retinol equivalents (RE)/d (2667 IU/d) for adult women and
1000 RE/d (3300 IU/d) for adult men; doses≥ 7500 RE (≥ 25000 IU)/d are considered
potentially toxic over the long term. Objective We assessed the safety in adults of long-term
vitamin A supplementation with doses above the daily biological need but< 7500 RE (< …
cancer and the degenerative eye disease retinitis pigmentosa. The daily biological need for
vitamin A is estimated to be 800 retinol equivalents (RE)/d (2667 IU/d) for adult women and
1000 RE/d (3300 IU/d) for adult men; doses≥ 7500 RE (≥ 25000 IU)/d are considered
potentially toxic over the long term. Objective We assessed the safety in adults of long-term
vitamin A supplementation with doses above the daily biological need but< 7500 RE (< …
