Effects of chronic renal failure on enzymes of energy metabolism in individual human muscle fibers.
A Conjard, B Ferrier, M Martin, A Caillette… - Journal of the …, 1995 - journals.lww.com
In order to improve knowledge about the mechanisms underlying the alterations of energy
metabolism recently observed in the skeletal muscle of patients suffering from chronic renal
failure, this study was designed to test (1) whether changes in the activity of key enzymes of
energy metabolism occur in the muscle of these patients, and if so (2) whether the different
muscle fiber types are equally altered in their metabolic machinery. For this, the maximum
activities of 14 enzymes were measured in individual muscle fibers microdissected from …
metabolism recently observed in the skeletal muscle of patients suffering from chronic renal
failure, this study was designed to test (1) whether changes in the activity of key enzymes of
energy metabolism occur in the muscle of these patients, and if so (2) whether the different
muscle fiber types are equally altered in their metabolic machinery. For this, the maximum
activities of 14 enzymes were measured in individual muscle fibers microdissected from …