Gastric emptying of varying meal weight and composition in man: Evaluation by dual liquid-and solid-phase isotopic method

JG Moore, PE Christian, RE Coleman - Digestive diseases and sciences, 1981 - Springer
JG Moore, PE Christian, RE Coleman
Digestive diseases and sciences, 1981Springer
Ten subjects were given self-selected filling meals (mean weight= 1692 g) and meals of 900
and 300 g. The three meals varied in composition and total kcal. Solid and liquid phase
gastric emptying was evaluated using 99m Tc-sulfur colloid-labeled chicken liver and [111
In] DTPA, and emptying was quantitated using the geometric mean of the anterior and
posterior counts. Emptying of the solid-phase marker was linear; mean half-emptying times
were 277 min, 146 min, and 77 min for the filling, 900-g, and 300-g meals, respectively …
Abstract
Ten subjects were given self-selected filling meals (mean weight=1692 g) and meals of 900 and 300 g. The three meals varied in composition and total kcal. Solid and liquid phase gastric emptying was evaluated using99mTc-sulfur colloid-labeled chicken liver and [ 111 In]DTPA, and emptying was quantitated using the geometric mean of the anterior and posterior counts. Emptying of the solid-phase marker was linear; mean half-emptying times were 277 min, 146 min, and 77 min for the filling, 900-g, and 300-g meals, respectively. Emptying of the liquid-phase marker was curvilinear, mean half-emptying times were 178 min, 81 min, and 40 min, for the filling, 900-g, and 300-g meals, respectively. Thus, meals of larger weight and kcal content were associated with longer emptying times for both solids and liquids.
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