Hypoglycemm Increases the Gastric Emptying Rate in Healthy Subjects
E Schvarcz, M Palmér, J Åman, C Berne - Diabetes Care, 1995 - Am Diabetes Assoc
E Schvarcz, M Palmér, J Åman, C Berne
Diabetes Care, 1995•Am Diabetes AssocOBJECTIVES To compare the gastric emptying rate during normoglycemia with that during
insulin-induced hypoglycemia in healthy subjects. RESEARCH DESIGN AND METHODS In
eight healthy subjects, the rate of gastric emptying of an isotope-labeled meal was assessed
by a scintigraphic technique during normoglycemia and hypoglycemia, both controlled by an
insulin-glucose clamp. RESULTS The mean time taken to empty 50% of the test meal from
the stomach (Tg0) for the solid phase was 43.0±20.0 min during normoglycemia, compared …
insulin-induced hypoglycemia in healthy subjects. RESEARCH DESIGN AND METHODS In
eight healthy subjects, the rate of gastric emptying of an isotope-labeled meal was assessed
by a scintigraphic technique during normoglycemia and hypoglycemia, both controlled by an
insulin-glucose clamp. RESULTS The mean time taken to empty 50% of the test meal from
the stomach (Tg0) for the solid phase was 43.0±20.0 min during normoglycemia, compared …
OBJECTIVES
To compare the gastric emptying rate during normoglycemia with that during insulin-induced hypoglycemia in healthy subjects.
RESEARCH DESIGN AND METHODS
In eight healthy subjects, the rate of gastric emptying of an isotope-labeled meal was assessed by a scintigraphic technique during normoglycemia and hypoglycemia, both controlled by an insulin-glucose clamp.
RESULTS
The mean time taken to empty 50% of the test meal from the stomach (Tg0) for the solid phase was 43.0 ± 20.0 min during normoglycemia, compared with 16.3 ± 6.6 min during hypoglycemia, P < 0.001. The mean T50 for the liquid phase was 38.0 ± 21.2 and 15.4 ± 10.6 min, respectively, P < 0.001.
CONCLUSIONS
Insulin-induced hypoglycemia increases the gastric emptying rate in healthy subjects.
Am Diabetes Assoc