Effect of alternate-day fasting on weight loss, weight maintenance, and cardioprotection among metabolically healthy obese adults: a randomized clinical trial
JF Trepanowski, CM Kroeger, A Barnosky… - JAMA internal …, 2017 - jamanetwork.com
Importance Alternate-day fasting has become increasingly popular, yet, to date, no long-term
randomized clinical trials have evaluated its efficacy. Objective To compare the effects of
alternate-day fasting vs daily calorie restriction on weight loss, weight maintenance, and risk
indicators for cardiovascular disease. Design, Setting, and Participants A single-center
randomized clinical trial of obese adults (18 to 64 years of age; mean body mass index, 34)
was conducted between October 1, 2011, and January 15, 2015, at an academic institution …
randomized clinical trials have evaluated its efficacy. Objective To compare the effects of
alternate-day fasting vs daily calorie restriction on weight loss, weight maintenance, and risk
indicators for cardiovascular disease. Design, Setting, and Participants A single-center
randomized clinical trial of obese adults (18 to 64 years of age; mean body mass index, 34)
was conducted between October 1, 2011, and January 15, 2015, at an academic institution …
