Choriocapillaris degeneration and related pathologic changes in human diabetic eyes

J Cao, DS McLeod, CA Merges… - Archives of …, 1998 - jamanetwork.com
Objectives To measure the extent of choriocapillaris degeneration (CCD) in diabetic
choroids and to study the association of CCD with choroidal neovascularization and
pathologic changes in Bruch's membrane–like basal laminar deposits. Materials and
Methods Human choroids from 10 postmortem subjects (diabetic, 5 [group 1]; nondiabetic, 5
[group 2]) were incubated for the histochemical demonstration of alkaline phosphatase and
nonspecific esterase activities, permitting analysis of the choroidal vasculature and …