Molecular and biochemical aspects of the PD-1 checkpoint pathway
VA Boussiotis - New England Journal of Medicine, 2016 - Mass Medical Soc
New England Journal of Medicine, 2016•Mass Medical Soc
Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway | New England Journal of
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Medicine Skip to main content The New England Journal of Medicine homepage Advanced
Search SEARCH SPECIALTIES Cardiology Clinical Medicine Emergency Medicine
Endocrinology Gastroenterology Hematology/Oncology Infectious Disease Nephrology
Neurology/Neurosurgery Obstetrics/Gynecology Pediatrics Pulmonary/Critical Care View All
Specialties TOPICS AI in Medicine Climate Crisis and Health Coronavirus Fundamentals of Health …
The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
