Relationship between insulin resistance, weight loss, and coronary heart disease risk in healthy, obese women

T McLaughlin, F Abbasi, HS Kim… - Metabolism …, 2001 - metabolismjournal.com
Several popular books have recently been published stating that being insulin-resistant
favors weight gain and/or prevents weight loss. Because this view seems to have gained
widespread support in the general population, we thought it important to perform the current
study testing the hypothesis that differences in insulin-mediated glucose disposal do not
affect weight loss in response to calorie-restricted diets. For this purpose, we studied the
change in weight and risk factors for coronary heart disease (CHD) in healthy women …