Human apolipoprotein A-IV metabolism within triglyceride-rich lipoproteins and plasma
Z Sun, AH Lichtenstein, GG Dolnikowski, FK Welty… - Atherosclerosis, 2001 - Elsevier
In order to investigate the metabolism of apo A-IV within TRL and plasma, we assessed TRL
and plasma apo A-IV kinetics in 19 and 4 subjects, respectively, consuming an average US
diet for a 6-week period. At the end of this diet study, each subject received a primed-
constant infusion of deuterated leucine over a 15 h time period with hourly feeding, and
blood samples were drawn at 10 time points. TRL was separated by ultracentrifugation. Apo
A-IV was isolated by immunoprecipitation and/or SDS-PAGE. Apo A-IV concentrations were …
and plasma apo A-IV kinetics in 19 and 4 subjects, respectively, consuming an average US
diet for a 6-week period. At the end of this diet study, each subject received a primed-
constant infusion of deuterated leucine over a 15 h time period with hourly feeding, and
blood samples were drawn at 10 time points. TRL was separated by ultracentrifugation. Apo
A-IV was isolated by immunoprecipitation and/or SDS-PAGE. Apo A-IV concentrations were …
