In vivo metabolism of apolipoprotein A-IV in severe hypertriglyceridemia: a combined radiotracer and stable isotope kinetic study.

B Verges, D Rader, J Schaefer, L Zech, M Kindt… - Journal of lipid …, 1994 - ASBMB
Apolipoprotein (apo) A-IV is an intestinally derived apolipoprotein that plays a potentially
important role in lipoprotein metabolism and reverse cholesterol transport. However, the
factors that regulate its plasma concentrations are not well understood. Plasma apoA-IV
levels have been previously shown to correlate with fasting triglyceride (TG) levels in
humans with TG levels less than 300 mg/dl (Lagrost et al. 1989. J. Lipid Res. 30: 701-710).
In this study, we established that apoA-IV levels were significantly elevated (mean 29.3 …