Risk factors of attacks in neuromyelitis optica spectrum disorders

T Akaishi, T Takahashi, K Fujihara, T Misu… - Journal of …, 2020 - Elsevier
Predisposing factors before the onset of neuromyelitis optica spectrum disorders (NMOSD)
have not been systematically evaluated by now. We investigated the detailed pre-onset
history in consecutive NMOSD patients. Thirteen of the enrolled 53 NMOSD patients (24.5%)
had accompanying autoimmune diseases, such as Sjögren's syndrome. History of
malignancy was seen in 8 of the 53 patients (15.1%). Recent history of non-neurological
clinical episodes, such as systemic allergic reaction, systemic infection, surgical operation …