The discovery of fibroblast growth factor 23 (FGF23) has provided a more complete
understanding of the regulation of phosphate and mineral homeostasis in health and in
chronic kidney disease. It has also offered new insights into stratification of risk of
cardiovascular events and death among patients with chronic kidney disease and the
general population. In this review, we provide an overview of FGF23 biology and physiology,
summarize clinical outcomes that have been associated with FGF23, discuss potential …