The relationship of Ca and P nutrition during adult life and osteoporosis in aged mice
BG Shah, GVG Krishnarao, HH Draper - The Journal of nutrition, 1967 - Elsevier
The influence of Ca and P intake throughout adult life on bone and soft tissue calcification
and the incidence of osteoporosis at senescence was investigated in mice. Animals were
maintained from 10 to 26 months of age with diets ranging from 0.1% to 2.4% in Ca and from
0.05% to 1.2% in P. When the Ca: P ratio was 2: 1, increases in dietary Ca were associated
with increments in ash content, cortical thickness, parabolic index and breaking load of the
femur. When the Ca: P ratio was 1: 1, these parameters were depressed and unresponsive …
and the incidence of osteoporosis at senescence was investigated in mice. Animals were
maintained from 10 to 26 months of age with diets ranging from 0.1% to 2.4% in Ca and from
0.05% to 1.2% in P. When the Ca: P ratio was 2: 1, increases in dietary Ca were associated
with increments in ash content, cortical thickness, parabolic index and breaking load of the
femur. When the Ca: P ratio was 1: 1, these parameters were depressed and unresponsive …