Insulin-like growth factor-1 and angiographically documented coronary artery disease
P Spallarossa, C Brunelli, F Minuto, D Caruso… - The American journal of …, 1996 - Elsevier
P Spallarossa, C Brunelli, F Minuto, D Caruso, M Battistini, S Caponnetto, R Cordera
The American journal of cardiology, 1996•ElsevierIn conclusion, we have reported an association between low IGF-I concentrations and CAD
in relatively young men. This observation raises the possibility that IGF-I deficiency could be
part of the polymetabolic syndrome. Whether a subnormal IGF-I production is due to growth
hormone secretory abnormalities or to other metabolic reasons (eg, insulin resistance or fat
distribution, or both) is still unknown.
in relatively young men. This observation raises the possibility that IGF-I deficiency could be
part of the polymetabolic syndrome. Whether a subnormal IGF-I production is due to growth
hormone secretory abnormalities or to other metabolic reasons (eg, insulin resistance or fat
distribution, or both) is still unknown.
In conclusion, we have reported an association between low IGF-I concentrations and CAD in relatively young men. This observation raises the possibility that IGF-I deficiency could be part of the polymetabolic syndrome. Whether a subnormal IGF-I production is due to growth hormone secretory abnormalities or to other metabolic reasons (e.g., insulin resistance or fat distribution, or both) is still unknown.
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