Neurobiological changes in the hippocampus during normative aging

JP Lister, CA Barnes - Archives of neurology, 2009 - jamanetwork.com
The number of individuals older than 65 years is projected to exceed 71.5 million in the year
2030, which is twice the number alive during the year 2000. While this dramatic increase in
the number of individuals at risk for Alzheimer and vascular disease will pose a significant
challenge to the health care industry, many older individuals will not actually die of these
age-related dementias. Instead, a significant proportion of those older than 65 years will
have to cope with alterations in memory function that are associated with normative aging. A …