Lipolysis is the biochemical pathway responsible for the catabolism of triacylglycerol (TAG)
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty
acids, which are subsequently used as energy substrates, essential precursors for lipid and
membrane synthesis, or mediators in cell signaling processes. Consistent with its central
importance in lipid and energy homeostasis, lipolysis occurs in essentially all tissues and
cell types, it is most abundant, however, in white and brown adipose tissue. Over the last …