[HTML][HTML] Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin …
JA Villena, S Roy, E Sarkadi-Nagy, KH Kim… - Journal of Biological …, 2004 - ASBMB
We have used rat cDNA microarrays to identify adipocyte-specific genes that could play an
important role in adipocyte differentiation or function. Here, we report the cloning and
identification of a 2.0-kb mRNA coding for a putative protein that we have designated as
desnutrin. The novel gene is expressed predominantly in adipose tissue, and its expression
is induced early during 3T3-L1 adipocyte differentiation. Desnutrin mRNA levels were
regulated by the nutritional status of animals, being transiently induced during fasting. In …
important role in adipocyte differentiation or function. Here, we report the cloning and
identification of a 2.0-kb mRNA coding for a putative protein that we have designated as
desnutrin. The novel gene is expressed predominantly in adipose tissue, and its expression
is induced early during 3T3-L1 adipocyte differentiation. Desnutrin mRNA levels were
regulated by the nutritional status of animals, being transiently induced during fasting. In …