[HTML][HTML] Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients
Neutralizing antibody (nAb) responses are attenuated in solid organ transplant recipients
(SOTRs) despite severe acute respiratory syndrome-coronavirus-2 vaccination.
Preexposure prophylaxis (PrEP) with the antibody combination tixagevimab and cilgavimab
(T+ C) might augment immunoprotection, yet in vitro activity and durability against Omicron
sublineages BA. 4/5 in fully vaccinated SOTRs have not been delineated. Vaccinated
SOTRs, who received 300+ 300 mg T+ C (ie, full dose), within a prospective observational …
(SOTRs) despite severe acute respiratory syndrome-coronavirus-2 vaccination.
Preexposure prophylaxis (PrEP) with the antibody combination tixagevimab and cilgavimab
(T+ C) might augment immunoprotection, yet in vitro activity and durability against Omicron
sublineages BA. 4/5 in fully vaccinated SOTRs have not been delineated. Vaccinated
SOTRs, who received 300+ 300 mg T+ C (ie, full dose), within a prospective observational …