Exhaled breath condensate eicosanoid levels associate with asthma and its severity

S Kazani, A Planaguma, E Ono, M Bonini… - Journal of allergy and …, 2013 - Elsevier
Background The relationship between anti-inflammatory lipoxins and proinflammatory
leukotrienes might be important in the pathobiology and severity of asthma. Objective We
sought to investigate whether exhaled breath condensate (EBC) lipoxin and leukotriene
measurements can noninvasively characterize the asthmatic diathesis and its severity.
Methods We measured lipoxin A 4 (LXA 4) and leukotriene B 4 (LTB 4) levels in EBC
collected from patients with asthma of different severities and from healthy control subjects …