Approach to overgrowth syndromes in the genome era
DD Burkardt, K Tatton‐Brown, W Dobyns… - American Journal of …, 2019 - Wiley Online Library
American Journal of Medical Genetics Part C: Seminars in Medical …, 2019•Wiley Online Library
This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the
current understanding of overgrowth syndromes. We clarify the terminology associated with
overgrowth, review some common pathways to overgrowth and present a preliminary
classification based on currently known genomic and epigenetic mechanisms. We introduce
the articles of this issue—new research and reviews of well‐established and recently
described overgrowth syndromes of the brain, body or both.
current understanding of overgrowth syndromes. We clarify the terminology associated with
overgrowth, review some common pathways to overgrowth and present a preliminary
classification based on currently known genomic and epigenetic mechanisms. We introduce
the articles of this issue—new research and reviews of well‐established and recently
described overgrowth syndromes of the brain, body or both.
Abstract
This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the current understanding of overgrowth syndromes. We clarify the terminology associated with overgrowth, review some common pathways to overgrowth and present a preliminary classification based on currently known genomic and epigenetic mechanisms. We introduce the articles of this issue—new research and reviews of well‐established and recently described overgrowth syndromes of the brain, body or both.
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