Estimated protection of prior SARS-CoV-2 infection against reinfection with the Omicron variant among messenger RNA–vaccinated and nonvaccinated individuals in …
Importance The Omicron variant is phylogenetically and antigenically distinct from earlier
SARS-CoV-2 variants and the original vaccine strain. Protection conferred by prior SARS-
CoV-2 infection against Omicron reinfection, with and without vaccination, requires
quantification. Objective To estimate the protection against Omicron reinfection and
hospitalization conferred by prior heterologous non-Omicron SARS-CoV-2 infection and/or
up to 3 doses of an ancestral, Wuhan-like messenger RNA (mRNA) vaccine. Design …
SARS-CoV-2 variants and the original vaccine strain. Protection conferred by prior SARS-
CoV-2 infection against Omicron reinfection, with and without vaccination, requires
quantification. Objective To estimate the protection against Omicron reinfection and
hospitalization conferred by prior heterologous non-Omicron SARS-CoV-2 infection and/or
up to 3 doses of an ancestral, Wuhan-like messenger RNA (mRNA) vaccine. Design …
