Corneal neovascularization (CNV) is a common sight-threatening pathology that can be
induced by a variety of inflammatory and angiogenic stimuli. Current CNV treatments include
anti-inflammatory drugs and antibody-based inhibitors of vascular endothelial growth factor
(VEGF). However, these are not always effective and novel therapeutic approaches are
needed. Previous work has indicated a role for nucleolin (NCL) in VEGF-mediated
neoangiogenesis in a suture-induced CNV model. The major goal for this current study is to …