Heavy metals released into the environment have a significant effect on respiratory health.
Lung macrophages are important in mounting an inflammatory response to injury, but they
are also involved in repair of injury. Macrophages develop mixed phenotypes in complex
pathological conditions and polarize to a predominant phenotype depending on the duration
and stage of injury and/or repair. Little is known about the reprogramming required for lung
macrophages to switch between these divergent functions; therefore, understanding the …