Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family
Establishment of skeletal muscle and neural cell types is controlled by families of myogenic
and neurogenic basic helix-loop-helix (bHLH) proteins, respectively. Myogenic bHLH
proteins have been shown to activate skeletal muscle transcription in collaboration with
members of the myocyte enhancer factor-2 (MEF2) family of MCM1-agamous-deficiens-
serum response factor (MADS)-box transcription factors, which are expressed in
differentiated myocytes and neurons. Here, we show that the neurogenic bHLH protein …
and neurogenic basic helix-loop-helix (bHLH) proteins, respectively. Myogenic bHLH
proteins have been shown to activate skeletal muscle transcription in collaboration with
members of the myocyte enhancer factor-2 (MEF2) family of MCM1-agamous-deficiens-
serum response factor (MADS)-box transcription factors, which are expressed in
differentiated myocytes and neurons. Here, we show that the neurogenic bHLH protein …
