Assessment of extent and role of tau in subcortical vascular cognitive impairment using 18F-AV1451 positron emission tomography imaging
Importance Amyloid-β (Aβ), tau, and cerebral small vessel disease (CSVD), which
occasionally coexist, are the most common causes of cognitive impairments in older people.
However, whether tau is observed in patients with subcortical vascular cognitive impairment
(SVCI), as well as its associations with Aβ and CSVD, are not yet established. More
importantly, the role of tau underlying cognitive impairments in SVCI is unknown. Objective
To investigate the extent and the role of tau in patients with SVCI using 18 F-AV1451, which …
occasionally coexist, are the most common causes of cognitive impairments in older people.
However, whether tau is observed in patients with subcortical vascular cognitive impairment
(SVCI), as well as its associations with Aβ and CSVD, are not yet established. More
importantly, the role of tau underlying cognitive impairments in SVCI is unknown. Objective
To investigate the extent and the role of tau in patients with SVCI using 18 F-AV1451, which …