The immune response in HPV+ oropharyngeal cancer
EV King, CH Ottensmeier, GJ Thomas - Oncoimmunology, 2014 - Taylor & Francis
EV King, CH Ottensmeier, GJ Thomas
Oncoimmunology, 2014•Taylor & FrancisAlthough human papillomavirus (HPV)+ oropharyngeal cancers often present with
metastasis, most patients have excellent long-term survival. The reason underlying such an
apparent contradiction remains unclear, but we have recently demonstrated that the
improved survival of HPV+ oropharyngeal cancer patients has an immunological
component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV+
patients into high-risk and low-risk groups.
metastasis, most patients have excellent long-term survival. The reason underlying such an
apparent contradiction remains unclear, but we have recently demonstrated that the
improved survival of HPV+ oropharyngeal cancer patients has an immunological
component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV+
patients into high-risk and low-risk groups.
Although human papillomavirus (HPV)+ oropharyngeal cancers often present with metastasis, most patients have excellent long-term survival. The reason underlying such an apparent contradiction remains unclear, but we have recently demonstrated that the improved survival of HPV+ oropharyngeal cancer patients has an immunological component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV+ patients into high-risk and low-risk groups.
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