Diabetes mellitus is associated with vascular complications including an impairment of
vascular function and alterations in the reactivity of blood vessels to vasoactive hormones.
However, the signaling mechanisms leading to vascular dysfunction in diabetes are not fully
understood. This microarray-based study was designed to identify differential gene
expression between the normal and diabetic mesenteric vasculature and to investigate the
effect of inhibiting epidermal growth factor receptor (EGFR) signaling on global gene …