Hemangioblastic foci in human first trimester placenta: distribution and gestational profile

JD Aplin, H Whittaker, YTJ Lim, S Swietlik, J Charnock… - Placenta, 2015 - Elsevier
Introduction The human placenta is a site of both hematopoiesis and vasculogenesis. There
are reports of hemangioblastic foci (HAF) in the first trimester placenta, but little published
information about their spatiotemporal incidence. Methods We have used semi-thin sections
and whole mount staining techniques on archival early pregnancy hysterectomy material as
well as freshly-collected termination tissue. Results We report a description of the
distribution of HAF, their gestational profile, and some characteristics of the constituent cells …