Calcium deposition within coronary atherosclerotic lesion: Implications for plaque stability
H Jinnouchi, Y Sato, A Sakamoto, A Cornelissen… - Atherosclerosis, 2020 - Elsevier
Atherosclerotic lesion progression is associated with intimal calcification. The earliest lesion
that shows calcification is pathologic intimal thickening in which calcifications appear as
microcalcifications that vary in size from< 0.5 to 15 μm. The calcifications become larger as
plaques progress, becoming punctate (> 15 μm to 1 mm in diameter), fragmented (> 1 mm),
and eventually sheet-like calcification (> 3 mm). When stratified by plaque type, maximum
calcifications are observed in fibrocalcific plaques, followed by healed plaque ruptures …
that shows calcification is pathologic intimal thickening in which calcifications appear as
microcalcifications that vary in size from< 0.5 to 15 μm. The calcifications become larger as
plaques progress, becoming punctate (> 15 μm to 1 mm in diameter), fragmented (> 1 mm),
and eventually sheet-like calcification (> 3 mm). When stratified by plaque type, maximum
calcifications are observed in fibrocalcific plaques, followed by healed plaque ruptures …