HIV-1-specific antibody responses during acute and chronic HIV-1 infection
GD Tomaras, BF Haynes - Current Opinion in HIV and AIDS, 2009 - journals.lww.com
GD Tomaras, BF Haynes
Current Opinion in HIV and AIDS, 2009•journals.lww.comThe antibody isotypes and specificities elicited during HIV-1 infection can provide a window
into deciphering the detrimental effects of HIV-1 on B cell and T cell responses. Additionally,
further characterization of the virus inhibitory capabilities of anti-HIV-1 antibody isotypes can
define the spectrum of potential protective HIV-1 antibodies that could be readily elicited by
experimental vaccines and adjuvants.
into deciphering the detrimental effects of HIV-1 on B cell and T cell responses. Additionally,
further characterization of the virus inhibitory capabilities of anti-HIV-1 antibody isotypes can
define the spectrum of potential protective HIV-1 antibodies that could be readily elicited by
experimental vaccines and adjuvants.
Summary
The antibody isotypes and specificities elicited during HIV-1 infection can provide a window into deciphering the detrimental effects of HIV-1 on B cell and T cell responses. Additionally, further characterization of the virus inhibitory capabilities of anti-HIV-1 antibody isotypes can define the spectrum of potential protective HIV-1 antibodies that could be readily elicited by experimental vaccines and adjuvants.
Lippincott Williams & Wilkins