Assessment of clinical criteria for sepsis: for the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

CW Seymour, VX Liu, TJ Iwashyna, FM Brunkhorst… - Jama, 2016 - jamanetwork.com
Importance The Third International Consensus Definitions Task Force defined sepsis as “life-
threatening organ dysfunction due to a dysregulated host response to infection.” The
performance of clinical criteria for this sepsis definition is unknown. Objective To evaluate
the validity of clinical criteria to identify patients with suspected infection who are at risk of
sepsis. Design, Settings, and Population Among 1.3 million electronic health record
encounters from January 1, 2010, to December 31, 2012, at 12 hospitals in southwestern …