Microvascular inflammation and acute tubular necrosis are major histologic features of hantavirus nephropathy
V Gnemmi, J Verine, L Vrigneaud, F Glowacki… - Human Pathology, 2015 - Elsevier
Hantavirus nephropathy (HVN) is an uncommon etiology of acute renal failure due to
hantavirus infection. Pathological features suggestive of HVN historically reported are
medullary interstitial hemorrhages in a background of acute interstitial nephritis (AIN).
However, interstitial hemorrhages may be lacking because of medullary sampling error. This
emphasizes that other pathological criteria may be of interest. We performed a retrospective
clinicopathological study of 17 serologically proven HVN cases with renal biopsy from 2 …
hantavirus infection. Pathological features suggestive of HVN historically reported are
medullary interstitial hemorrhages in a background of acute interstitial nephritis (AIN).
However, interstitial hemorrhages may be lacking because of medullary sampling error. This
emphasizes that other pathological criteria may be of interest. We performed a retrospective
clinicopathological study of 17 serologically proven HVN cases with renal biopsy from 2 …