Mouse models for infectious diseases caused by Staphylococcus aureus
HK Kim, D Missiakas, O Schneewind - Journal of immunological methods, 2014 - Elsevier
Staphylococcus aureus–a commensal of the human skin, nares and gastrointestinal tract–is
also a leading cause of bacterial skin and soft tissue infection (SSTIs), bacteremia, sepsis,
peritonitis, pneumonia and endocarditis. Antibiotic-resistant strains, designated MRSA
(methicillin-resistant S. aureus), are common and represent a therapeutic challenge. Current
research and development efforts seek to address the challenge of MRSA infections through
vaccines and immune therapeutics. Mice have been used as experimental models for S …
also a leading cause of bacterial skin and soft tissue infection (SSTIs), bacteremia, sepsis,
peritonitis, pneumonia and endocarditis. Antibiotic-resistant strains, designated MRSA
(methicillin-resistant S. aureus), are common and represent a therapeutic challenge. Current
research and development efforts seek to address the challenge of MRSA infections through
vaccines and immune therapeutics. Mice have been used as experimental models for S …