Animal models: murine cytomegalovirus
J Podlech, R Holtappels, NKA Grzimek… - Methods in …, 2002 - Elsevier
Publisher Summary This chapter focuses on murine cytomegalovirus (CMV) animal models.
Multiple-organ cytomegalovirus disease, interstitial pneumonia in particular, is a major
concern in the therapy of hematopoietic malignancies by hematoablative treatment and
bone marrow transplantation (BMT). Human CMV (hCMV) is the prototype member of the
subfamily, Betaherpesvirinae, of the virus family, Herpesviridae. Its genome is a linear,
double-stranded DNA with a coding capacity of ca. 165 open reading frames. During an …
Multiple-organ cytomegalovirus disease, interstitial pneumonia in particular, is a major
concern in the therapy of hematopoietic malignancies by hematoablative treatment and
bone marrow transplantation (BMT). Human CMV (hCMV) is the prototype member of the
subfamily, Betaherpesvirinae, of the virus family, Herpesviridae. Its genome is a linear,
double-stranded DNA with a coding capacity of ca. 165 open reading frames. During an …