Antidepressant remission to dTMS of the dmPFC and ACC in lateral PFC dTMS nonresponders: case series

A Tendler, E Sisko, N Barnea-Ygael… - … Clinical Research in …, 2017 - brainstimjrnl.com
Over the last decade, the FDA approved two different TMS coils for treatment resistant
depression (TRD) patients. These coils, namely the figure-8 rTMS coil and the H1 deep
rTMS (dTMS) coil, differ in some aspects, but are both used in MDD patients to target
primarily the left dorsolateral prefrontal cortex (L-DLPFC). Yet, the current stimulation
protocols fail to benefit a large population of TRD patients, probably due to the heterogeneity
of the disorder, which affects multiple cortical and subcortical networks [1]. As such, novel …