Safety, tolerability and effectiveness of a novel 20 Hz rTMS protocol targeting dorsomedial prefrontal cortex in major depression: an open-label case series
Repetitive transcranial magnetic stimulation (rTMS) of the dorsomedial prefrontal cortex
(DMPFC) in treatment-resistant depression (TRD) has been recently studied as an
alternative to conventional dorsolateral prefrontal cortex (DLPFC) rTMS [1, 2]. Across both
targets, intermittent theta-burst stimulation (iTBS) reduces treatment duration while achieving
comparable outcomes to conventional 10 Hz stimulation [1, 3]. However, iTBS can require
more costly devices than conventional high-frequency rTMS, and the consistency of …
(DMPFC) in treatment-resistant depression (TRD) has been recently studied as an
alternative to conventional dorsolateral prefrontal cortex (DLPFC) rTMS [1, 2]. Across both
targets, intermittent theta-burst stimulation (iTBS) reduces treatment duration while achieving
comparable outcomes to conventional 10 Hz stimulation [1, 3]. However, iTBS can require
more costly devices than conventional high-frequency rTMS, and the consistency of …