Background Depression is a heterogeneous mental illness. Neurostimulation treatments, by
targeting specific nodes within the brain's emotion-regulation network, may be useful both as
therapies and as probes for identifying clinically relevant depression subtypes. Methods
Here, we applied 20 sessions of magnetic resonance imaging-guided repetitive transcranial
magnetic stimulation (rTMS) to the dorsomedial prefrontal cortex in 47 unipolar or bipolar
patients with a medication-resistant major depressive episode. Results Treatment response …