Is intrinsic asthma synonymous with infection?
PE Dahlberg, WW Busse - Clinical & Experimental Allergy, 2009 - Wiley Online Library
PE Dahlberg, WW Busse
Clinical & Experimental Allergy, 2009•Wiley Online LibraryRackemann described the 'intrinsic asthma'population over 50 years ago as a unique
subgroup that was characterized by onset of progressive loss of lung function beginning
later in life, possibly after a respiratory infection. It has also been associated with a female
predominance, aspirin‐sensitive bronchospasm, and nasal polyposis. While the aetiology is
not understood, we propose that persistent respiratory infections play a central role in the
development of intrinsic asthma.
subgroup that was characterized by onset of progressive loss of lung function beginning
later in life, possibly after a respiratory infection. It has also been associated with a female
predominance, aspirin‐sensitive bronchospasm, and nasal polyposis. While the aetiology is
not understood, we propose that persistent respiratory infections play a central role in the
development of intrinsic asthma.
Summary
Rackemann described the ‘intrinsic asthma’ population over 50 years ago as a unique subgroup that was characterized by onset of progressive loss of lung function beginning later in life, possibly after a respiratory infection. It has also been associated with a female predominance, aspirin‐sensitive bronchospasm, and nasal polyposis. While the aetiology is not understood, we propose that persistent respiratory infections play a central role in the development of intrinsic asthma.
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