Gastric microbiota

G Ianiro, J Molina‐Infante, A Gasbarrini - Helicobacter, 2015 - Wiley Online Library
G Ianiro, J Molina‐Infante, A Gasbarrini
Helicobacter, 2015Wiley Online Library
After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a
sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of
the gastric mucosa. Using culture‐independent methods of analysis, a non‐H. pylori
microbial community has been recently observed in the human stomach, the so‐called
human gastric microbiota, along with H. pylori itself. Increasing evidence supports the
hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial …
Abstract
After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture‐independent methods of analysis, a non‐H. pylori microbial community has been recently observed in the human stomach, the so‐called human gastric microbiota, along with H. pylori itself. Increasing evidence supports the hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial culprit leading to gastric diseases. Further studies are warranted to offer a better picture of the role and functions of gastric microbiota and to identify the best therapeutic modulators of gut microbiota for the management of gastric diseases.
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